SCHEMBL16256504

SCHEMBL16256504

C=C(C)C(=O)NCCSCCNC(=O)C(C)(C)CC

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
RIPK1 Q13546 3/20 0.36
DRD2 P14416 2/20 0.33
DRD4 P21917 2/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10033554 0.89 RIPK1 (0.41) RIPK1DRD2DRD4
SCHEMBL12716899 0.83 RIPK1 (0.37) RIPK1DRD2DRD4
SCHEMBL16256501 0.79 RIPK1 (0.35) RIPK1DRD2DRD4
SCHEMBL7754063 0.78 TSHR (0.48) TSHRALDH1A1
SCHEMBL16256499 0.78 DRD2 (0.36) RIPK1DRD2DRD4
SCHEMBL16256506 0.78 THRB (0.35) TSHRRIPK1DRD2DRD4ALDH1A1
SCHEMBL12286425 0.77 TSHR (0.44) TSHRALDH1A1
SCHEMBL18141323 0.76 TSHR (0.52) TSHRALDH1A1
SCHEMBL7780928 0.76 RIPK1 (0.39) TSHRRIPK1DRD2DRD4
SCHEMBL29068843 0.76 POLB (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9690195-B2 Lithographic printing plate precursors and processes for preparing lithographic printing plates FUJIFILM CORPORATION (JP) 2017-06-27 US disclosed
US-20150044612-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND PROCESSES FOR PREPARING LITHOGRAPHIC PRINTING PLATES FUJIFILM CORPORATION (JP) 2015-02-12 US disclosed
US-8895224-B2 Lithographic printing plate precursors and processes for preparing lithographic printing plates FUJIFILM CORPORATION (JP) 2014-11-25 US disclosed