Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239984 | 0.89 | ALOX15 (0.38) | KMT2AALDH1A1POLBALOX15PARP1 | |
| SCHEMBL15151532 | 0.87 | CREBBP (0.47) | KMT2AALDH1A1ALOX15PARP1CREBBP | |
| SCHEMBL16240177 | 0.85 | KMT2A (0.62) | KMT2AALDH1A1POLBNPSR1TSHR | |
| SCHEMBL4471417 | 0.85 | ALDH1A1 (0.44) | KMT2AALDH1A1POLBCREBBPNPSR1 | |
| SCHEMBL16240138 | 0.83 | MAPT (0.36) | KMT2AALDH1A1POLBALOX15CREBBP | |
| SCHEMBL16240140 | 0.83 | MAPT (0.36) | KMT2AALDH1A1POLBALOX15CREBBP | |
| SCHEMBL15151468 | 0.79 | PARP1 (0.42) | KMT2AALDH1A1POLBALOX15PARP1 | |
| SCHEMBL16257625 | 0.78 | ALDH1A1 (0.55) | KMT2AALDH1A1POLBNPSR1TSHR | |
| SCHEMBL16270877 | 0.76 | L3MBTL1 (0.34) | KMT2AALDH1A1POLBNPC1RAB9A | |
| SCHEMBL15151528 | 0.75 | KMT2A (0.48) | KMT2AALDH1A1POLBNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343017-A1 | PYRROLE COMPOUND | TUBB3, TUBB1, TUBB | KMT2A 2038/4885ALDH1A1 2354/4885POLB 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.