Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 14/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.38 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244703 | 0.86 | HDAC4 (0.42) | HDAC4HDAC1SMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL8249384 | 0.84 | F2 (0.37) | HDAC4HDAC1XIAPBIRC3BIRC2 | |
| SCHEMBL6382019 | 0.84 | F2 (0.37) | HDAC4HDAC1XIAPBIRC3BIRC2 | |
| SCHEMBL7919172 | 0.82 | BIRC3 (0.39) | HDAC4HDAC1XIAPBIRC3BIRC2 | |
| SCHEMBL16258958 | 0.80 | OPRM1 (0.34) | HDAC4HDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19870556 | 0.78 | BIRC3 (0.36) | HDAC4HDAC1XIAPBIRC3BIRC2 | |
| SCHEMBL7932107 | 0.74 | PPIA (0.33) | HDAC4HDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14170128 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14169970 | 0.69 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL8239491 | 0.69 | BACE1 (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018028634-A1 | SALTS AS HCV INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-02-15 | — | — | WO | disclosed |