Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 3/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258958 | 0.84 | OPRM1 (0.34) | PSMB9HDAC4HDAC1PSMB8MAPT | |
| SCHEMBL8244703 | 0.76 | HDAC4 (0.42) | HDAC4HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19869647 | 0.74 | HDAC4 (0.38) | HDAC4HDAC1MAPTKDM4EALDH1A1 | |
| SCHEMBL7923887 | 0.73 | PSMB9 (0.32) | PPIAPSMB9PSMB8MAPTKDM4E | |
| SCHEMBL8249384 | 0.68 | F2 (0.37) | HDAC4HDAC1GAA | |
| SCHEMBL6382019 | 0.68 | F2 (0.37) | HDAC4HDAC1GAA | |
| SCHEMBL7919172 | 0.67 | BIRC3 (0.39) | HDAC4HDAC1 | |
| SCHEMBL4304535 | 0.62 | PSMB9 (0.41) | PSMB9PSMB8 | |
| SCHEMBL12472216 | 0.61 | PSMB9 (0.37) | PSMB9HDAC4HDAC1PSMB8CYP2C9 | |
| SCHEMBL13951691 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033466-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE | PHENOMIX CORPORATION (US) | 2010-03-25 | — | — | WO | disclosed |