Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC3 | Q13489 | 5/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.39 |
| ▸ | TERF2 | Q15554 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249384 | 0.82 | F2 (0.37) | BIRC3XIAPBIRC2HDAC4HDAC1 | |
| SCHEMBL6382019 | 0.82 | F2 (0.37) | BIRC3XIAPBIRC2HDAC4HDAC1 | |
| SCHEMBL19869647 | 0.82 | HDAC4 (0.38) | BIRC3XIAPBIRC2HDAC4HDAC1 | |
| SCHEMBL19870556 | 0.77 | BIRC3 (0.36) | BIRC3XIAPBIRC2TERF2HDAC4 | |
| SCHEMBL8244703 | 0.77 | HDAC4 (0.42) | HDAC4HDAC1HDAC6 | |
| SCHEMBL16258958 | 0.72 | OPRM1 (0.34) | HDAC4HDAC1 | |
| SCHEMBL8239491 | 0.72 | BACE1 (0.33) | — | |
| SCHEMBL13435807 | 0.69 | — | — | |
| SCHEMBL1655875 | 0.67 | BIRC3 (0.38) | BIRC3XIAPBIRC2TERF2HDAC4 | |
| SCHEMBL12820532 | 0.67 | MEN1 (0.36) | BIRC3XIAPBIRC2TERF2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088394-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-08-05 | — | — | WO | disclosed |