Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16261160 | 0.87 | MEN1 (0.47) | EPHX2NR1H4LMNARAB9AMEN1 | |
| SCHEMBL2341110 | 0.83 | LMNA (0.47) | EPHX2NR1H4CYP2C19CYP2C9LMNA | |
| SCHEMBL16448820 | 0.82 | AOC3 (0.46) | EPHX2NR1H4LMNARAB9ACA1 | |
| SCHEMBL4874599 | 0.81 | MTOR (0.58) | CYP2C19CYP2C9MTOR | |
| SCHEMBL2827305 | 0.81 | EPHX2 (0.69) | EPHX2NR1H4CYP2C19CYP2C9LMNA | |
| SCHEMBL14672763 | 0.80 | TACR1 (0.42) | EPHX2NR1H4LMNARAB9AHDAC3 | |
| SCHEMBL27792864 | 0.79 | GSR (0.54) | CYP2C19CYP2C9LMNARECQLMEN1 | |
| SCHEMBL16449102 | 0.77 | MEN1 (0.44) | EPHX2NR1H4MEN1KMT2ACA1 | |
| SCHEMBL14764199 | 0.76 | TSHR (0.54) | EPHX2NR1H4CYP2C19LMNARAB9A | |
| SCHEMBL2387771 | 0.76 | RXRA (0.50) | EPHX2NR1H4LMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | PCNA, TIMCC, SGTA | EPHX2 4627/4885NR1H4 3574/4885CYP2C19 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.