Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 5/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | STAT6 | P42226 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BCL3 | P20749 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263912 | 0.85 | BCL3 (0.42) | MAPTMEN1KMT2AJAK2KCNH2 | |
| SCHEMBL19494912 | 0.81 | CFTR (0.40) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL16263849 | 0.80 | CNR2 (0.42) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL16338625 | 0.79 | CFTR (0.48) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL19494312 | 0.76 | MEN1 (0.32) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL19494633 | 0.76 | ALDH1A1 (0.33) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL16263801 | 0.74 | L3MBTL1 (0.47) | MAPTSMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL16263844 | 0.73 | KDM1A (0.36) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL16337492 | 0.69 | CFTR (0.47) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL19494707 | 0.67 | NPC1 (0.40) | MAPTSMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014180562-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS | GALAPAGOS NV (BE) | 2014-11-13 | — | — | WO | disclosed |