Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263912 | 0.91 | BCL3 (0.42) | MEN1KMT2AHTTLMNATP53 | |
| SCHEMBL19494912 | 0.81 | CFTR (0.40) | CNR2MEN1KMT2AHTTLMNA | |
| SCHEMBL16263934 | 0.80 | MAPT (0.33) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL16246467 | 0.79 | MEN1 (0.50) | CNR2MEN1KMT2ATP53ENPP2 | |
| SCHEMBL19494903 | 0.76 | CNR2 (0.39) | CNR2EPHX2MEN1KMT2AHTT | |
| SCHEMBL16263801 | 0.76 | L3MBTL1 (0.47) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL19494633 | 0.76 | ALDH1A1 (0.33) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL16263844 | 0.75 | KDM1A (0.36) | CNR2EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16261720 | 0.74 | RAB9A (0.47) | CNR2MEN1KMT2ALMNATP53 | |
| SCHEMBL19494707 | 0.73 | NPC1 (0.40) | MEN1KMT2AHTTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014180562-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS | GALAPAGOS NV (BE) | 2014-11-13 | — | — | WO | disclosed |