Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995586 | 0.88 | TSHR (0.50) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL172668 | 0.83 | TSHR (0.54) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL6219972 | 0.80 | TRPA1 (0.59) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL16209876 | 0.80 | CARM1 (0.55) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL4530889 | 0.80 | DNM1 (0.54) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL25234019 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL1006191 | 0.80 | CARM1 (0.55) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL3211466 | 0.80 | CARM1 (0.55) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL4530213 | 0.80 | DNM1 (0.54) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL18890757 | 0.78 | CARM1 (0.48) | TSHRALDH1A1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014190096-A1 | COMPOSITIONS AND METHODS COMPRISING A POLYAMINE | CURZA GLOBAL, LLC (US) | 2014-11-27 | — | — | WO | disclosed |