Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16209876 | 0.83 | CARM1 (0.55) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL16264696 | 0.83 | TSHR (0.56) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL14578374 | 0.83 | CARM1 (0.60) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL4530889 | 0.83 | DNM1 (0.54) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL4530213 | 0.83 | DNM1 (0.54) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL25234019 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL3211466 | 0.83 | CARM1 (0.55) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL13995586 | 0.83 | TSHR (0.50) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL1006191 | 0.83 | CARM1 (0.55) | TSHRALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL18436476 | 0.82 | ADRA2B (0.67) | TSHRALDH1A1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081805-B1 | Signaling compositions, methods, and systems for effecting plant growth and crop enhancement | KamTec, LLC (US) | 2018-09-25 | — | — | US | claimed |
| US-20140283198-A1 | Signaling Compositions, Methods, and Systems for Effecting Plant Growth and Crop Enhancement | KamTec, LLC (US) | 2014-09-18 | — | — | US | claimed |
| US-20140283199-A1 | Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement | KamTec (US) | 2014-09-18 | — | — | US | claimed |
| JP-2005538978-A | — | — | 2005-12-22 | — | — | JP | claimed |
| EP-1523474-A1 | CRYSTALLINE FORMS OF IMIDOALKANPERCARBOXYLIC ACIDS | Solvay Solexis S.p.A. (IT) | 2005-04-20 | — | — | EP | claimed |
| WO-2004007452-A1 | CRYSTALLINE FORMS OF IMIDOALKANPERCARBOXYLIC ACIDS | SOLVAY SOLEXIS S.P.A. (IT) | 2004-01-22 | — | — | WO | claimed |
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230050819-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-02-16 | — | — | US | disclosed |
| US-10940139-B2 | Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease | SHY Therapeutics LLC (US) | 2021-03-09 | — | — | US | disclosed |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200121660-A1 | COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, INC. | 2020-04-23 | — | — | US | disclosed |
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-04-11 | — | — | US | disclosed |
| US-10081805-B1 | Signaling compositions, methods, and systems for effecting plant growth and crop enhancement | KamTec, LLC (US) | 2018-09-25 | — | — | US | disclosed |
| EP-1955697-A1 | 2-AMINOBENZAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20070208049-A1 | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-7196106-B2 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | MERCK & CO., INC (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196106-B2 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | MERCK & CO., INC (US) | 2007-03-27 | — | — | US | disclosed |
| US-6951958-B1 | Solid phase parallel synthesis of tertiary amines | ACADIA PHARMACEUTICALS INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040097552-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2004-05-20 | — | — | US | disclosed |
| US-20040097552-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | POLRMT, RNASE1, POLM | TSHR 3661/4885ALDH1A1 2389/4885CARM1 2332/4885 |
| US-20040097552-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | GLP1R, GPR119, GCGR | TSHR 106/4885ALDH1A1 2652/4885CARM1 4213/4885 |
| US-20200121660-A1 | COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | HRAS, KRAS, NRAS | TSHR 4307/4885ALDH1A1 3448/4885CARM1 2593/4885 |
| US-20230050819-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | CYFIP2, TPX2, ATXN2 | TSHR 1535/4885ALDH1A1 4788/4885CARM1 1812/4885 |
| US-10940139-B2 | Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease | HRAS, KRAS, NRAS | TSHR 4307/4885ALDH1A1 3448/4885CARM1 2593/4885 |
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | HAVCR2, HMBS, VHL | TSHR 3784/4885ALDH1A1 172/4885CARM1 1158/4885 |
| US-20070208049-A1 | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto | GNRHR, GHRHR, LHCGR | TSHR 53/4885ALDH1A1 3443/4885CARM1 3355/4885 |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | POLRMT, RNASE1, POLM | TSHR 3661/4885ALDH1A1 2389/4885CARM1 2332/4885 |
| US-20140283199-A1 | Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement | BOLA2; BOLA2B, DBNL, EBPL | TSHR 2361/4885ALDH1A1 3134/4885CARM1 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.