SCHEMBL16265334

SCHEMBL16265334

CC(C)(Oc1ccc(NC(=O)c2cc(C(=O)Nc3ccc(OC(C)(C)C(=O)O)cc3)cc(C(=O)Nc3ccc(C(=O)C(C)(C)C(=O)O)cc3)c2)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.49
PPARA Q07869 10/20 0.47
PPARG P37231 4/20 0.47
FABP2 P12104 2/20 0.47
SLC22A12 Q96S37 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C19 P33261 1/20 0.46
TP53 P04637 1/20 0.46
ALOX15 P16050 1/20 0.46
ALDH1A1 P00352 1/20 0.43
PPARD Q03181 1/20 0.43
DGAT1 O75907 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265137 0.92 TRPV1 (0.43) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL16265333 0.91 PPARA (0.54) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL16743455 0.85 PPARA (0.50) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL16265332 0.82 PGR (0.60) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL804816 0.82 TRPV1 (0.46) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL9130742 0.82 PPARA (0.59) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL16743652 0.81 NPC1 (0.64) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL16743452 0.81 RAB9A (0.71) TRPV1SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL12166209 0.80 PPARA (0.69) TRPV1PPARAPPARGFABP2SLC22A12
SCHEMBL14976928 0.80 NPC1 (0.67) NPC1RAB9AMEN1KMT2ADGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040553-B2 Phenoxyisobutyric acid compounds and method of synthesis Cell Viable Corporation (US) 2015-05-26 US disclosed
US-20140350045-A1 PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS LALEZARI IRAJ (US) 2014-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350045-A1 PHENOXYISOBUTYRIC ACID COMPOUNDS AND METHOD OF SYNTHESIS AGER, BPGM, PDXK TRPV1 3677/4885PPARA 262/4885PPARG 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.