Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864977 | 0.89 | ABHD6 (0.49) | PTGDR2ALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL16268884 | 0.84 | PTGDR2 (0.52) | PTGDR2ALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL28534873 | 0.83 | HRH3 (0.47) | PTGDR2MEN1KMT2ANOTUMHPGD | |
| SCHEMBL30641865 | 0.82 | DRD2 (0.51) | KMT2ANOTUMHSD17B10KDM4E | |
| SCHEMBL19599364 | 0.81 | ADRA2A (0.60) | ALDH1A1S1PR5PRMT5WDR77RXRA | |
| SCHEMBL3479749 | 0.77 | RXRB (0.66) | POLBHSD17B10KDM4ECD69TSHR | |
| SCHEMBL28245905 | 0.76 | TAAR1 (0.40) | ALDH1A1MEN1KMT2ANOTUMPARP1 | |
| SCHEMBL28548896 | 0.76 | RXRB (0.64) | PTGDR2POLBHSD17B10KDM4ECD69 | |
| SCHEMBL18586143 | 0.75 | PTGDR2 (0.41) | PTGDR2ALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL30726807 | 0.75 | ALDH1A1 (0.51) | PTGDR2ALDH1A1MEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263924-B | Cxcr7 receptor modulators | 爱杜西亚制药有限公司 | 2018-10-19 | — | — | CN | disclosed |
| EP-3004082-A1 | CXCR7 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd. (CH) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014191929-A1 | CXCR7 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2014-12-04 | — | — | WO | disclosed |