SCHEMBL1627428

SCHEMBL1627428

C1CCCCCCCCCCCCOOCCCCCCCCCCC1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4284256 1.00
SCHEMBL3806170 1.00
SCHEMBL4278304 1.00
SCHEMBL1135196 1.00 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL861286 1.00 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL1080333 1.00
Cyclohexane SCHEMBL10618057 1.00 ALDH1A1 (0.42) ALDH1A1TSHR
Cyclopentane SCHEMBL7775480 1.00 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL11125555 1.00 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL5820312 1.00 ALDH1A1 (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180020811-A1 BRUSH FOR COSMETIC IMPLEMENTS AND MANUFACTURING METHOD OF THE SAME MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2018-01-25 US disclosed
EP-3272248-A2 BRUSH FOR COSMETIC PRODUCTS AND MANUFACTURING METHOD OF THE SAME Mitsubishi Pencil Company, Limited (JP) 2018-01-24 EP disclosed
EP-3067041-A1 METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE Shisei Chemical Co., Ltd. (JP) 2016-09-14 EP disclosed
CN-104379836-B The manufacture method of softening agent for paper, paper and sanitary paper 星光PMC株式会社 2016-06-22 CN disclosed
EP-1505139-B2 THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME SHISEIDO CO LTD (JP) 2014-06-18 EP disclosed
US-20140100327-A1 (METH)ACRYLIC ACID-BASED COPOLYMER SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2014-04-10 US disclosed
CN-103562241-A (meth)acrylic acid-based copolymer SUMITOMO SEIKA CHEMICALS 2014-02-05 CN disclosed
EP-1505139-B1 THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME SHISEIDO CO LTD (JP) 2011-07-13 EP disclosed
US-20110098231-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2011-04-28 US disclosed
US-7927615-B2 Thickener, cosmetic preparation containing the same, and process for producing the same SHISEIDO COMPANY, LTD. (JP) 2011-04-19 US disclosed
EP-2168568-A1 SKIN COSMETIC Shiseido Company, Limited (JP) 2010-03-31 EP disclosed
US-20100029787-A1 Thickener, Cosmetic Preparation Containing The Same, And Process For Producing The Same SHISEIDO COMPANY, LTD. (JP) 2010-02-04 US disclosed
US-20090258964-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2009-10-15 US disclosed
US-20050175564-A1 Tickener, cosmetic preparation containing the same, and process for producing the same SHISEIDO COMPANY, LTD. (JP) 2005-08-11 US disclosed
EP-1505139-A1 THICKENER, COSMETIC PREPARATION CONTAINING THE SAME, AND PROCESS FOR PRODUCING THE SAME SHISEIDO COMPANY, LTD. (JP) 2005-02-09 EP disclosed
EP-0308543-B1 COMPOSITIONS FOR EXTERNAL APPLICATION Sansho Seiyaku Co., Ltd. (JP) 1993-09-22 EP disclosed
US-4948577-A KOJIC ACID AND 4-/1,1-DIMETHYLETHYL/-4'-METHOXY DIBENZOYLMETHANE; PREVENT COLORING OF SKIN WHEN EXPOSED TO ULTRAVIOLET LIGHT SANSHO SEIYAKU CO., LTD. (JP) 1990-08-14 US disclosed
EP-0308543-A1 Compositions for external application Sansho Seiyaku Co., Ltd. (JP) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050175564-A1 Tickener, cosmetic preparation containing the same, and process for producing the same TRHDE, FN1, SAMM50 ALDH1A1 4031/4885TSHR 1314/4885
US-20090258964-A1 Skin Cosmetic CUTA, DEGS1, ALAD ALDH1A1 1951/4885TSHR 4285/4885
US-20100029787-A1 Thickener, Cosmetic Preparation Containing The Same, And Process For Producing The Same POLD1, FASN, PCNA ALDH1A1 3259/4885TSHR 2594/4885
US-20110098231-A1 Skin Cosmetic CUTA, DEGS1, ALAD ALDH1A1 1951/4885TSHR 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.