SCHEMBL16282199

SCHEMBL16282199

COc1cc(N(c2ccccc2)c2ccc3ccccc3c2)ccc1-c1ccc(N(c2ccccc2)c2ccc3ccccc3c2)c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
CRHR1 P34998 2/20 0.38
NQO1 P15559 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
EGFR P00533 1/20 0.35
PDGFRB P09619 1/20 0.35
KDR P35968 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17999996 0.92 SLC16A3 (0.42) MAPTCYP1A2CYP2A6SLC16A3SLC16A1
SCHEMBL16282214 0.90 TSHR (0.40) MAPTCYP2A6CRHR1NQO1EGFR
SCHEMBL16282209 0.89 CRHR1 (0.34) MAPTCYP1A2CYP2A6SLC16A3SLC16A1
SCHEMBL8051257 0.88 KDM4E (0.35) MAPTCYP1A2CYP2A6MEN1KMT2A
SCHEMBL12888150 0.86 KDM4E (0.34) MAPTCYP1A2CYP2A6MEN1KMT2A
SCHEMBL18000000 0.85 ERN1 (0.35) MAPTCYP1A2CYP2A6KDRRAB9A
SCHEMBL14069709 0.83 ALDH1A1 (0.32) MAPTCYP1A2CYP2A6MEN1KMT2A
SCHEMBL1753896 0.83 KDM4E (0.37) MAPTCYP1A2CYP2A6KDM4EALDH1A1
SCHEMBL17999999 0.83 LPL (0.42) MAPT
SCHEMBL16282210 0.83 INSR (0.37) MAPTCYP1A2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9425416-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-23 US disclosed
US-9425416-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-23 US disclosed
US-20140361266-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed
US-20140361266-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-11 US disclosed