Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630189 | 1.00 | CYP2D6 (0.43) | CYP2D6ADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL15870309 | 0.98 | CYP2D6 (0.45) | CYP2D6ADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL15870315 | 0.93 | AR (0.39) | CYP2D6ADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL1628870 | 0.91 | AR (0.38) | CYP2D6ADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL12222349 | 0.81 | ADRB2 (0.46) | CYP2D6ADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL1628525 | 0.77 | PLA2G2A (0.45) | ADRB2ADRB1ADRB3CYP1A2ALOX15 | |
| SCHEMBL1628873 | 0.77 | PLA2G2A (0.45) | ADRB2ADRB1ADRB3CYP1A2ALOX15 | |
| SCHEMBL12222339 | 0.77 | FFAR1 (0.46) | ADRB2ADRB1ADRB3CYP1A2ALOX15 | |
| SCHEMBL12222354 | 0.76 | PLA2G2A (0.46) | ADRB2ADRB1ADRB3CYP1A2ALOX15 | |
| SCHEMBL12978498 | 0.74 | LMNA (0.45) | CYP2D6ADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194025-A1 | Production of Highly Concentrated Solutions of Self-Assembling Proteins | FREUDENBERG FORSCHUNGSDIENSTE KG (DE) | 2014-07-10 | — | — | US | disclosed |
| US-20120085262-A1 | Production of Highly Concentrated Solutions of Self-Assembling Proteins | FREUDENBERG FORSCHUNGSDIENSTE KG (DE) | 2012-04-12 | — | — | US | disclosed |