SCHEMBL16285335

SCHEMBL16285335

c1ccc(Nc2ccc3c(c2)Oc2cc(Nc4ccccc4)ccc2N3)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
MAPT P10636 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
AR P10275 1/20 0.48
HSD17B10 Q99714 4/20 0.48
ALOX12 P18054 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
ALOX15 P16050 3/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
ALOX5 P09917 2/20 0.47
CYP3A4 P08684 4/20 0.46
HPGD P15428 2/20 0.46
GNG2 P59768 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424622 0.84 MAPT (0.44) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL2389452 0.80 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2AAR
SCHEMBL21511294 0.79 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2AAR
SCHEMBL22825075 0.79 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2AAR
SCHEMBL28428230 0.77 L3MBTL1 (0.51) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL23281155 0.74 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2AAR
SCHEMBL14535169 0.74 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2AAR
SCHEMBL12199657 0.74 GNG2 (0.49) ALDH1A1MAPTMEN1KMT2AAR
Phenoxazine SCHEMBL28318942 0.73 ALOX5 (0.55) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL11693706 0.71 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9529261-B2 Color-forming composition, color-forming curable composition, lithographic printing plate precursor and plate making method, and color-forming compound FUJIFILM CORPORATION (JP) 2016-12-27 US disclosed
US-9529261-B2 Color-forming composition, color-forming curable composition, lithographic printing plate precursor and plate making method, and color-forming compound FUJIFILM CORPORATION (JP) 2016-12-27 US disclosed
US-20140360395-A1 COLOR-FORMING COMPOSITION, COLOR-FORMING CURABLE COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD, AND COLOR-FORMING COMPOUND FUJIFILM CORPORATION (JP) 2014-12-11 US disclosed