SCHEMBL162855

SCHEMBL162855

CCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@@H](C=C(CO)C[C@]3(O)C(=O)C(C)=C[C@@H]23)[C@H]2C(C)(C)[C@]12OC(=O)CCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 1.00
PRKCG P05129 5/20 1.00
PRKCB P05771 5/20 1.00
PRKCH P24723 5/20 1.00
PRKCE Q02156 5/20 1.00
PRKCQ Q04759 5/20 1.00
PRKCD Q05655 5/20 1.00
PRKD3 O94806 4/20 1.00
PRKCI P41743 4/20 1.00
PRKCZ Q05513 4/20 1.00
PRKD1 Q15139 4/20 1.00
VAV1 P15498 2/20 1.00
USP2 O75604 2/20 0.80
TP53 P04637 2/20 0.80
KDM4E B2RXH2 1/20 0.80
ALDH1A1 P00352 1/20 0.80
SMN1; SMN2 Q16637 1/20 0.80
CYP3A4 P08684 1/20 0.80
CYP2C9 P11712 1/20 0.80
TSHR P16473 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26309957 1.00 PRKCA (1.00) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL29366787 1.00 PRKCA (1.00) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL8750573 1.00 PRKCA (1.00) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL2411275 0.94 PRKCA (0.95) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL18399995 0.94 PRKCA (0.95) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL31109155 0.94 PRKCA (0.95) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL295345 0.94 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL29353576 0.94 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL1568997 0.94 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE
SCHEMBL3211990 0.94 PRKCA (0.94) PRKCAPRKCGPRKCBPRKCHPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041660-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms CHANG RICHARD L (US) 2026-02-12 US claimed
US-12539289-B2 Phorbol ester compositions and methods of use for treating or reducing the duration of cytopenia BIOSUCCESS BIOTECH COMPANY, LIMITED (US) 2026-02-03 US claimed
WO-2025235403-A1 DIFFERENTIATION OF PANCREATIC ISLET CELLS VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-11-13 WO claimed
US-20250332115-A1 CONTROLLED EXPRESSION OF THERAPEUTICALLY RELEVANT BIOMOLECULES FOR LUMEN-LOCALIZED PAYLOADS IN BIOMIMETIC NANOVESICLES AND EXOSOMES MALCOLM THOMAS (US) 2025-10-30 US claimed
WO-2025072196-A1 METHODS FOR CULTURING AND ASSAYING B CELL LYMPHOCYTES BRUKER CELLULAR ANALYSIS, INC. (US) 2025-04-03 WO claimed
EP-2804601-B1 PHORBOL ESTER compounds for use in the treatment of neoplastic diseases BIOSUCCESS BIOTECH CO LTD (US) 2025-04-02 EP claimed
US-20250092360-A1 METHODS AND COMPOSITIONS FOR GENERATING SOMATOSTATIN+ INTERNEURONS FROM HUMAN FOREBRAIN NEURAL PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. 2025-03-20 US claimed
US-20240382532-A1 STEM CELL DERIVED PANCREATIC ISLET DIFFERENTIATION VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-11-21 US claimed
US-20240358767-A1 STEM CELL DIFFERENTIATION AND CHEMICAL COMPOUNDS VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-10-31 US claimed
US-20240294879-A1 STEM CELL DIFFERENTIATION AND POLYMERS VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-09-05 US claimed
WO-1997020212-A1 TREATMENT OF INFLAMMATION BY INHIBITION OF LIPID BODY FORMATION BETH ISRAEL DEACONESS MEDICAL CENTER (US) 1997-06-05 WO claimed
EP-0457295-B1 Use of a modulator of protein phosphorylation in the treatment of amyloidosis associated with Alzheimer's disease UNIV ROCKEFELLER (US) 1997-04-09 EP claimed
EP-0752867-A1 SELECTIVE CELL PROLIFERATION HEMOSOL INC. (CA) 1997-01-15 EP claimed
US-5385915-A Using an enzyme inhibitor THE ROCKEFELLER UNIVERSITY (US) 1995-01-31 US claimed
WO-1994016715-A1 SELECTIVE CELL PROLIFERATION HEMOSOL, INC. (CA) 1994-08-04 WO claimed
EP-0457295-A2 Use of a modulator of protein phosphorylation in the treatment of amyloidosis associated with Alzheimer's disease THE ROCKEFELLER UNIVERSITY (US) 1991-11-21 EP claimed
EP-0291728-A2 Production of immune interferon and its mRNA MELOY LABORATORIES, INC. (US) 1988-11-23 EP claimed
EP-0139878-A2 Production of immune interferon and its mRNA MELOY LABORATORIES, INC. (US) 1985-05-08 EP claimed
EP-0137691-A1 Production of immune interferon and its mRNA MELOY LABORATORIES, INC. (US) 1985-04-17 EP claimed
EP-0063482-A2 Production of immune interferon and its mRNA MELOY LABORATORIES, INC. (US) 1982-10-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240382532-A1 STEM CELL DERIVED PANCREATIC ISLET DIFFERENTIATION IAPP, PNLIP, ALPG PRKCA 53/4885PRKCG 48/4885PRKCB 25/4885
US-20260041660-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms TSLP, MAVS, PLAA PRKCA 32/4885PRKCG 102/4885PRKCB 115/4885
US-12539289-B2 Phorbol ester compositions and methods of use for treating or reducing the duration of cytopenia MYD88, EBP, IL2 PRKCA 45/4885PRKCG 154/4885PRKCB 37/4885
US-20240358767-A1 STEM CELL DIFFERENTIATION AND CHEMICAL COMPOUNDS EBP, AKT3, PRKCD PRKCA 11/4885PRKCG 24/4885PRKCB 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.