SCHEMBL18157316

SCHEMBL18157316

CCOP(C)(=O)Cc1ccc(Br)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KCNH2 Q12809 1/20 0.35
NR1I2 O75469 2/20 0.34
PKM P14618 1/20 0.34
POLB P06746 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
ACHE P22303 1/20 0.33
GAA P10253 1/20 0.33
NPBWR1 P48145 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC22A12 Q96S37 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18157311 0.86 LMNA (0.38) LMNAL3MBTL1KDM4EHPGDCNR1
SCHEMBL18157324 0.82 KDM4E (0.37) LMNAKDM4EHPGDCNR1CNR2
SCHEMBL10146809 0.78 ACP3 (0.56) LMNAL3MBTL1KDM4EHPGDNR1I2
SCHEMBL11751939 0.75 KDM4E (0.44) LMNAKDM4EHPGDNPSR1KCNH2
SCHEMBL1628637 0.75 TSHR (0.34) LMNANPSR1KCNH2POLBGAA
SCHEMBL31596398 0.74 LMNA (0.45) LMNAL3MBTL1KDM4ECNR1CNR2
SCHEMBL11893022 0.74 LMNA (0.45) LMNAL3MBTL1KDM4ECNR1CNR2
SCHEMBL16974734 0.73 MEN1 (0.44) LMNAL3MBTL1KDM4EHPGDNPSR1
SCHEMBL12911121 0.72 CA2 (0.44) LMNAKDM4EHPGDACHE
SCHEMBL16984761 0.71 ALDH1A1 (0.48) LMNAL3MBTL1KDM4EHPGDCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663447-B2 Asymmetric butadiene-based charge transport compound, electrophotographic photoreceptor containing same, and image forming apparatus S-PRINTING SOLUTION CO., LTD. (KR) 2017-05-30 US disclosed
US-20160304437-A1 ASYMMETRIC BUTADIENE-BASED CHARGE TRANSPORT COMPOUND, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME, AND IMAGE FORMING APPARATUS SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304437-A1 ASYMMETRIC BUTADIENE-BASED CHARGE TRANSPORT COMPOUND, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME, AND IMAGE FORMING APPARATUS ALDH1A2, USE1, SLC9A1 LMNA 2243/4885L3MBTL1 3742/4885KDM4E 4458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.