SCHEMBL16289537

SCHEMBL16289537

[CH2]c1ccc2cc(C(F)(F)F)ccc2n1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.62
▸ HRH3 Q9Y5N1 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.44
▸ EPHX2 P34913 1/20 0.42
▸ SCN4A P35499 1/20 0.42
▸ METAP2 P50579 1/20 0.41
▸ PDE1A P54750 1/20 0.40
▸ PDE1B Q01064 1/20 0.40
▸ PDE4B Q07343 1/20 0.40
▸ PDE7A Q13946 1/20 0.40
▸ NPBWR1 P48145 2/20 0.38
▸ PDE10A Q9Y233 1/20 0.38
▸ ESR1 P03372 1/20 0.37
▸ DGAT1 O75907 2/20 0.36
▸ KCNH2 Q12809 2/20 0.36
▸ CCNE2 O96020 1/20 0.36
▸ CCNA2 P20248 1/20 0.36
▸ CCNE1 P24864 1/20 0.36
▸ CDK2 P24941 1/20 0.36
▸ CCNA1 P78396 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30586443 0.78 BACE1 (0.65) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL10967442 0.78 BACE1 (0.65) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL5090080 0.77 BACE1 (0.62) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL29746263 0.77 BACE1 (0.68) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL20660645 0.77 BACE1 (0.62) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL1721620 0.77 BACE1 (0.68) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL5683005 0.77 BACE1 (1.00) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL13356605 0.77 BACE1 (0.62) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL5479064 0.77 BACE1 (0.57) BACE1HRH3KDM4EEPHX2SCN4A
SCHEMBL28070145 0.74 BACE1 (0.59) BACE1HRH3KDM4EEPHX2SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 — — EP disclosed
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 — — CN disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 — — EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 — — US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 — — US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 — — EP disclosed
CN-106572659-A Noxious arthropod control agent containing amide compound 住友化学株式会社 2017-04-19 — — CN disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 — — CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 — — US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 — — CN disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 — — US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 — — EP disclosed
CN-104105694-A Amide compound and use thereof for pest control SUMITOMO CHEMICAL CO 2014-10-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 BACE1 1913/4885HRH3 45/4885KDM4E 1006/4885
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL RPS8, MT-CO2, ARG1 BACE1 2892/4885HRH3 32/4885KDM4E 1028/4885
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 BACE1 3869/4885HRH3 76/4885KDM4E 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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