SCHEMBL1629035

SCHEMBL1629035

C=Cc1ccc(C[N+](CCCC)(CCCC)CCCC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRNA7 P36544 3/20 0.42
▸ CHRNB4 P30926 2/20 0.42
▸ CHRNA3 P32297 2/20 0.42
▸ CHRNB2 P17787 1/20 0.42
▸ CHRNA4 P43681 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.39
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ SLC22A1 O15245 2/20 0.38
▸ TAS1R3 Q7RTX0 1/20 0.36
▸ TAS1R1 Q7RTX1 1/20 0.36
▸ PSMD14 O00487 1/20 0.36
▸ HSP90AA1 P07900 1/20 0.36
▸ MMP2 P08253 1/20 0.36
▸ MC4R P32245 1/20 0.36
▸ RAD52 P43351 1/20 0.36
▸ DNM1 Q05193 2/20 0.35
▸ KCNH2 Q12809 3/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2791842 0.98 CHRNA7 (0.41) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL26460127 0.95 PSMD14 (0.43) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL26460073 0.95 CHRNA7 (0.49) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL18256109 0.95 PSMD14 (0.41) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL19873339 0.94 CHRNA7 (0.39) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL788817 0.94 CHRNA7 (0.39) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL18256178 0.93 PSMD14 (0.44) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL26460075 0.93 CHRNA7 (0.47) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL25369277 0.92 PSMD14 (0.46) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL28644851 0.92 PSMD14 (0.46) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024106024-A1 TEMPERATURE-RESPONSIVE IONIC LIQUID, TRANSDERMAL ABSORPTION ENHANCING AGENT OR TRANSDERMAL ABSORPTION-ENHANCING AID INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID, AND PHARMACEUTICAL COMPOSITION INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID 東レ株式会社 2024-05-23 — — WO disclosed
US-20240058452-A1 PHARMACEUTICAL COMPOSITION CONTAINING TEMPERATURE-RESPONSIVE IONIC LIQUID TORAY INDUSTRIES, INC. (JP) 2024-02-22 — — US disclosed
CN-114502142-B Pharmaceutical composition comprising temperature responsive ionic liquid 东丽株式会社 2023-05-09 — — CN disclosed
US-20230101362-A1 RNA STABILIZATION TEAM MEDICAL LLC 2023-03-30 — — US disclosed
WO-2023044455-A2 RNA STABILIZATION TEAM MEDICAL LLC (US) 2023-03-23 — — WO disclosed
EP-4043007-A1 PHARMACEUTICAL COMPOSITION INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID Toray Industries, Inc. (JP) 2022-08-17 — — EP disclosed
CN-114502142-A Pharmaceutical compositions comprising temperature-responsive ionic liquids 东丽株式会社 2022-05-13 — — CN disclosed
WO-2021070893-A1 PHARMACEUTICAL COMPOSITION INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID 東レ株式会社 2021-04-15 — — WO disclosed
CN-107429047-B Polyester resin composition and method for producing same 东丽株式会社 2020-01-21 — — CN disclosed
US-8022397-B2 Transistor SEIKO EPSON CORPORATION (JP) 2011-09-20 — — US disclosed
US-7927913-B2 Electrolyte pattern and method for manufacturing an electrolyte pattern SEIKO EPSON CORPORATION (JP) 2011-04-19 — — US disclosed
US-20090039343-A1 Transistor SEIKO EPSON CORPORATION (JP) 2009-02-12 — — US disclosed
US-20090042346-A1 Electrolyte pattern and method for manufacturing an electrolyte pattern SEIKO EPSON CORPORATION (JP) 2009-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058452-A1 PHARMACEUTICAL COMPOSITION CONTAINING TEMPERATURE-RESPONSIVE IONIC LIQUID SULT1A1, CYP2C19, SULT2A1 CHRNA7 3164/4885CHRNB4 4350/4885CHRNA3 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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