Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28644851 | 0.98 | PSMD14 (0.46) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL25369277 | 0.98 | PSMD14 (0.46) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL18256109 | 0.98 | PSMD14 (0.41) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL26460127 | 0.95 | PSMD14 (0.43) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL2791842 | 0.95 | CHRNA7 (0.41) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL1629035 | 0.93 | CHRNA7 (0.42) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Thiocyanic Acid SCHEMBL18256170 | 0.90 | HTT (0.37) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL26460073 | 0.88 | CHRNA7 (0.49) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL2788608 | 0.88 | CHRNA7 (0.44) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL19873339 | 0.87 | CHRNA7 (0.39) | PSMD14HSP90AA1MMP2MC4RRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11458453-B2 | Molecularly imprinted polymer beads for extraction of metals and uses thereof | 6th Wave Innovations Corp. (US) | 2022-10-04 | — | — | US | disclosed |
| US-11389782-B2 | Molecularly imprinted polymer beads for extraction of lithium, mercury, and scandium | 6th Wave Innovations Corp. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20210252477-A1 | MOLECULARLY IMPRINTED POLYMER BEADS FOR EXTRACTION OF METALS AND USES THEREOF | ORCA HOLDINGS, LLC | 2021-08-19 | — | — | US | disclosed |
| US-11000844-B2 | Ion exchange resins selective for the complexation of univalent anions in aqueous solutions | TechSource, Inc. (US) | 2021-05-11 | — | — | US | disclosed |
| US-10814306-B2 | Molecularly imprinted polymer beads for extraction of metals and uses thereof | 6th Wave Innovations Corp. (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3535054-A1 | MOLECULARLY IMPRINTED POLYMER BEADS FOR EXTRACTION OF LITHIUM, MERCURY, AND SCANDIUM | 6th Wave Innovations Corp. (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20190232272-A1 | ION EXCHANGE RESINS SELECTIVE FOR THE COMPLEXATION OF UNIVALENT ANIONS IN AQUEOUS SOLUTIONS | TechSource, Inc. (US) | 2019-08-01 | — | — | US | disclosed |
| US-10252259-B2 | Ion exchange resins selective for the complexation of univalent anions in aqueous solutions | TechSource, Inc. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180214845-A1 | MOLECULARLY IMPRINTED POLYMER BEADS FOR EXTRACTION OF METALS AND USES THEREOF | ORCA HOLDINGS, LLC | 2018-08-02 | — | — | US | disclosed |
| EP-3328539-A1 | MOLECULARLY IMPRINTED POLYMER BEADS FOR EXTRACTION OF METALS AND USES THEREOF | 6th Wave Innovations Corp. (US) | 2018-06-06 | — | — | EP | disclosed |
| US-20180117564-A1 | MOLECULARLY IMPRINTED POLYMER BEADS FOR EXTRACTION OF LITHIUM, MERCURY, AND SCANDIUM | ORCA HOLDINGS, LLC | 2018-05-03 | — | — | US | disclosed |
| WO-2016196847-A1 | ION EXCHANGE RESINS SELECTIVE FOR THE COMPLEXATION OF UNIVALENT ANIONS IN AQUEOUS SOLUTIONS | TechSource, Inc. (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20160354770-A1 | Ion Exchange Resins Selective for the Complexation of Univalent Anions in Aqueous Solutions | TECHSOURCE, LLC | 2016-12-08 | — | — | US | disclosed |
| US-9504988-B1 | Molecularly imprinted polymer beads for extraction of metals and uses thereof | 6th Wave Innovations Corp. (US) | 2016-11-29 | — | — | US | disclosed |