Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28644851 | 1.00 | PSMD14 (0.46) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL18256178 | 0.98 | PSMD14 (0.44) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL26460127 | 0.97 | PSMD14 (0.43) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL18256109 | 0.97 | PSMD14 (0.41) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL2791842 | 0.93 | CHRNA7 (0.41) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL1629035 | 0.92 | CHRNA7 (0.42) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Thiocyanic Acid SCHEMBL18256170 | 0.88 | HTT (0.37) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL26460073 | 0.87 | CHRNA7 (0.49) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL2788608 | 0.86 | CHRNA7 (0.44) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Hydrochloric Acid SCHEMBL2208780 | 0.86 | HSP90AA1 (0.65) | PSMD14HSP90AA1MMP2MC4RRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12455275-B2 | Non-enzymatic sensor element with selectivity and non-enzymatic sensor | NATIONAL TSING HUA UNIVERSITY (TW) | 2025-10-28 | — | — | US | disclosed |
| US-20230273184-A1 | NON-ENZYMATIC SENSOR ELEMENT WITH SELECTIVITY AND NON-ENZYMATIC SENSOR | NATIONAL TSING HUA UNIVERSITY (TW) | 2023-08-31 | — | — | US | disclosed |