Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | UBE2N | P61088 | 1/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 7/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31262899 | 1.00 | KDM4E (0.80) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL946372 | 0.89 | KDM4E (1.00) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL29694480 | 0.89 | KDM4E (1.00) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL9667769 | 0.83 | KDM4E (0.74) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL3622901 | 0.82 | KDM4E (0.58) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL3615167 | 0.81 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL3615171 | 0.81 | HTR6 (0.78) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL7828911 | 0.81 | CA2 (0.71) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL7828914 | 0.81 | CA2 (0.71) | KDM4EUBE2NL3MBTL1CA2CA9 | |
| SCHEMBL11909017 | 0.81 | CA2 (0.71) | KDM4EUBE2NL3MBTL1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008078-B1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES BOSTON COLLEGE (US) | 2018-12-19 | — | — | EP | disclosed |
| US-9938253-B2 | Catalysts for efficient Z-selective metathesis | TRUSTEES OF BOSTON COLLEGE (US) | 2018-04-10 | — | — | US | disclosed |
| EP-3008078-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | Trustees of Boston College (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014201300-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | ADH5, ADH1A, ADH1C | KDM4E 2167/4885UBE2N 3072/4885L3MBTL1 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.