Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.33 |
| ▸ | GLI2 | P10070 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293919 | 0.90 | TRPV1 (0.39) | EGFRTRPV1ERCC1ERCC4PTGS2 | |
| SCHEMBL1629294 | 0.88 | EGFR (0.41) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL4854736 | 0.81 | EGFR (0.43) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL872522 | 0.81 | EGFR (0.43) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL328706 | 0.81 | ALOX5 (0.41) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL10272267 | 0.81 | ALOX5 (0.41) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL13013439 | 0.80 | EGFR (0.48) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL872574 | 0.78 | EGFR (0.40) | EGFRTYRALOX5FFAR1PTGS2 | |
| SCHEMBL13013000 | 0.78 | FFAR1 (0.43) | EGFRALOX5FFAR1PTGS2 | |
| SCHEMBL11822461 | 0.77 | ALOX5 (0.43) | EGFRTYRALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143324-B2 | antioxidants with hindered phenol functionality perform better in curing of polybenzocyclobutene materials in air without undue degradation of key properties | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-27 | — | — | US | disclosed |