SCHEMBL16294237

SCHEMBL16294237

CC(=O)c1ccc(CC(N)=O)s1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
LMNA P02545 3/20 0.50
RECQL P46063 2/20 0.50
PRNP P04156 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
GSK3B P49841 1/20 0.47
HPGD P15428 4/20 0.46
TSHR P16473 1/20 0.44
PTGES O14684 1/20 0.42
PLAU P00749 1/20 0.40
MAPT P10636 5/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
USP2 O75604 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1707142 0.82 HPGD (0.61) ALDH1A1KMT2AMEN1LMNARECQL
Methane SCHEMBL7759142 0.81 HPGD (0.59) ALDH1A1KMT2AMEN1LMNARECQL
SCHEMBL11235459 0.80 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1LMNARECQL
SCHEMBL10209862 0.78 HPGD (0.63) ALDH1A1KMT2AMEN1LMNARECQL
SCHEMBL1798146 0.78 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL5351604 0.78 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL11631412 0.76 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL4096475 0.76 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL17065257 0.76 GSK3B (0.60) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL16563807 0.75 SMN1; SMN2 (0.49) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2026-04-23 US disclosed
US-12448355-B2 Acetyl-CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2025-10-21 US disclosed
US-20210246106-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2021-08-12 US disclosed
US-10995070-B2 Acetyl-CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2021-05-04 US disclosed
US-20190135757-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2019-05-09 US disclosed
US-10207995-B2 Acetyl CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2019-02-19 US disclosed
US-20160145212-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2016-05-26 US disclosed
WO-2014201327-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2014-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246106-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, ACAT2 ALDH1A1 1039/4885KMT2A 1738/4885MEN1 4484/4885
US-12448355-B2 Acetyl-CoA carboxylase modulators ACACA, ACACB, ACAT2 ALDH1A1 1039/4885KMT2A 1738/4885MEN1 4484/4885
US-20160145212-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, ACAT2 ALDH1A1 1039/4885KMT2A 1738/4885MEN1 4484/4885
US-10207995-B2 Acetyl CoA carboxylase modulators ACACA, ACACB, ACAT2 ALDH1A1 1076/4885KMT2A 1917/4885MEN1 4468/4885
US-20190135757-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, ACAT2 ALDH1A1 1039/4885KMT2A 1738/4885MEN1 4484/4885
US-10995070-B2 Acetyl-CoA carboxylase modulators ACACA, ACACB, ACAT2 ALDH1A1 1039/4885KMT2A 1738/4885MEN1 4484/4885
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, HACL2 ALDH1A1 1026/4885KMT2A 3187/4885MEN1 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.