Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | PRNP | P04156 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707142 | 0.98 | HPGD (0.61) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL9067494 | 0.82 | HPGD (0.65) | HPGDKMT2AALDH1A1RECQLMAPT | |
| SCHEMBL16294237 | 0.81 | ALDH1A1 (0.51) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL68973 | 0.79 | HPGD (0.59) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL2332754 | 0.78 | MAPT (0.59) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL10209862 | 0.78 | HPGD (0.63) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL5351604 | 0.78 | ALDH1A1 (0.54) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL1798146 | 0.78 | ALDH1A1 (0.56) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL11680962 | 0.77 | KMT2A (0.59) | HPGDKMT2AALDH1A1RECQLLMNA | |
| SCHEMBL13838138 | 0.77 | LMNA (0.88) | HPGDKMT2AALDH1A1RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748802-B1 | Process for the preparation of alpha-methyl-2-thiopheneacetic acid derivatives | ERREGIERRE SPA (IT) | 2001-03-28 | — | — | EP | disclosed |
| US-5650522-A | MULTISTAGE PROCESS TO FORM KETONE, THEN REACTION WITH HALODIESTER COMPOUND TO FORM KETOTHIOPHENEDIESTER THEN SAPONIFICATION WITH ALKALI AND MINERAL ACID | ERREGIERRE S.P.A. (IT) | 1997-07-22 | — | — | US | disclosed |
| EP-0748802-A1 | Process for the preparation of alpha-methyl-2-thiopheneacetic acid derivatives | ERREGIERRE S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |