Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359030 | 0.80 | TSHR (0.44) | CRHR1TSHRMAPTNPSR1CYP3A4 | |
| SCHEMBL3146133 | 0.77 | NQO2 (0.44) | CRHR1NQO2MAPTNPSR1LMNA | |
| SCHEMBL12671987 | 0.76 | NQO2 (0.41) | CRHR1NQO2TUBB1TUBB4ATUBB | |
| SCHEMBL28323262 | 0.74 | ACHE (0.52) | NQO2MAPTNPSR1AMY1ALMNA | |
| SCHEMBL850590 | 0.73 | MTNR1A (0.39) | LMNAPDE3BPDE3AL3MBTL1SMN1; SMN2 | |
| SCHEMBL14609613 | 0.72 | TUBB4A (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19976319 | 0.72 | TSHR (0.41) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL23580916 | 0.71 | ALOX5 (0.55) | NQO2MAPTNPSR1AMY1ACYP3A4 | |
| SCHEMBL9290124 | 0.71 | NQO2 (0.46) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL1911939 | 0.71 | NQO2 (0.50) | NQO2TUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |