Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358668 | 0.88 | — | — | |
| SCHEMBL849342 | 0.79 | S1PR4 (0.41) | SYK | |
| SCHEMBL16104804 | 0.79 | PDK1 (0.33) | — | |
| SCHEMBL13390260 | 0.75 | RXRA (0.50) | — | |
| SCHEMBL850950 | 0.75 | MGLL (0.39) | SYK | |
| SCHEMBL12619052 | 0.75 | TRPV4 (0.49) | — | |
| SCHEMBL1798366 | 0.73 | RXRA (0.47) | — | |
| SCHEMBL16302614 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL16302578 | 0.72 | AAK1 (0.36) | — | |
| SCHEMBL16358671 | 0.69 | S1PR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |