Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 2/20 | 0.50 |
| ▸ | WHR1 | P49842 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346993 | 0.88 | MAPT (0.51) | NR4A1WHR1ALDH1A1MAPTGAA | |
| SCHEMBL15358685 | 0.85 | NR4A1 (0.61) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL31353138 | 0.84 | NR4A1 (0.49) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL13723749 | 0.84 | NR4A1 (0.49) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL23126654 | 0.82 | DRD2 (0.48) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL1930522 | 0.82 | ALDH1A1 (0.59) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL16305337 | 0.81 | LGMN (0.47) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL15244255 | 0.81 | NR4A1 (0.47) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL3166854 | 0.81 | ALDH1A1 (0.59) | NR4A1ALDH1A1ALDH1A3MAPTGAA | |
| SCHEMBL15540924 | 0.80 | NR4A1 (0.51) | NR4A1ALDH1A1ALDH1A3MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |