SCHEMBL163054

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL164014	0.83	ADORA3 (0.45)	HTTRAB9AHCAR3SMN1; SMN2MAPK1
	SCHEMBL162816	0.77	HDAC3 (0.43)	HCAR3MAPK1ALDH1A1CYP2C9HCAR2
	SCHEMBL160431	0.76	RAB9A (0.48)	KMT2AHTTRAB9ASMN1; SMN2NPC1
	SCHEMBL164683	0.74	BAZ2B (0.42)	RAB9AHCAR3MAPK1NPC1TP53
	SCHEMBL162591	0.74	HDAC3 (0.48)	L3MBTL1RAB9ASMN1; SMN2NPC1TP53
	SCHEMBL163376	0.73	JAK2 (0.44)	KMT2AMEN1HTTL3MBTL1RAB9A
	SCHEMBL164699	0.73	RAB9A (0.58)	KMT2AMEN1RAB9ASMN1; SMN2MAPK1
	SCHEMBL5768524	0.73	KMT2A (0.48)	KMT2AMEN1HTTL3MBTL1RAB9A
	SCHEMBL162312	0.72	HDAC3 (0.52)	KMT2AHTTRAB9AHCAR3SMN1; SMN2
	SCHEMBL164373	0.72	GABRA1 (0.45)	KMT2AL3MBTL1HCAR3MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.