Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 3/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 3/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.39 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.39 |
| ▸ | LHCGR | P22888 | 1/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834389 | 0.87 | RARB (0.39) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16305638 | 0.86 | L3MBTL1 (0.46) | ESRRGESRRBGCGRADCY6ADCY3 | |
| SCHEMBL16306026 | 0.86 | CTSS (0.37) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16294595 | 0.82 | GCGR (0.53) | ESRRGESRRBGCGRADCY6ADCY3 | |
| SCHEMBL16294330 | 0.82 | GCGR (0.53) | ESRRGESRRBGCGRADCY6ADCY3 | |
| SCHEMBL17834444 | 0.81 | ESRRG (0.35) | ESRRGESRRBGCGRADCY6ADCY3 | |
| SCHEMBL15037181 | 0.81 | CA1 (0.53) | ESRRGESRRBLHCGRL3MBTL1CTSL | |
| SCHEMBL16306015 | 0.80 | TDP1 (0.42) | ESRRGLHCGRKIFC1L3MBTL1CTSS | |
| SCHEMBL22384129 | 0.80 | TDP1 (0.42) | ESRRGLHCGRKIFC1L3MBTL1CTSS | |
| SCHEMBL17834436 | 0.79 | RARB (0.42) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |
| WO-2014201172-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2014-12-18 | — | — | WO | disclosed |