Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.36 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.35 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.35 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.35 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.35 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.35 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834436 | 0.92 | RARB (0.42) | RARBGCGRITGB3ITGA2BADCY6 | |
| SCHEMBL22384056 | 0.88 | L3MBTL1 (0.41) | RARBGCGRITGB3ITGA2BSUCNR1 | |
| SCHEMBL16305639 | 0.88 | L3MBTL1 (0.41) | RARBGCGRITGB3ITGA2BSUCNR1 | |
| SCHEMBL16306004 | 0.87 | ESRRG (0.40) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16306026 | 0.87 | CTSS (0.37) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL16294773 | 0.85 | GCGR (0.48) | RARBGCGRITGB3ITGA2BADCY6 | |
| SCHEMBL16294771 | 0.85 | GCGR (0.48) | RARBGCGRITGB3ITGA2BADCY6 | |
| SCHEMBL22384055 | 0.83 | L3MBTL1 (0.42) | GCGRITGB3ITGA2BADCY6ADCY3 | |
| SCHEMBL16305939 | 0.83 | GCGR (0.48) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL22384306 | 0.81 | RARB (0.46) | RARBITGB3ITGA2BPLGKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |