Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MYB | P10242 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763980 | 0.83 | MAPT (0.58) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3698426 | 0.81 | POLB (0.46) | MAPTALDH1A1TSHRCYP2A6HSD17B10 | |
| SCHEMBL16307954 | 0.81 | MAPT (0.44) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2201698 | 0.80 | ALDH1A1 (0.42) | MAPTCYP1A2ALDH1A1TSHRCYP2A6 | |
| SCHEMBL26033936 | 0.77 | ALDH1A1 (0.39) | MAPTCYP1A2ALDH1A1TSHRCYP2A6 | |
| SCHEMBL8490846 | 0.77 | CYP3A4 (0.37) | MAPTCYP1A2ALDH1A1TSHRCYP2A6 | |
| SCHEMBL9310776 | 0.77 | SLC2A1 (0.43) | MAPTALDH1A1TSHRCYP2A6HSD17B10 | |
| SCHEMBL10553536 | 0.76 | TLR8 (0.44) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3274765 | 0.76 | MAPT (0.47) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL27740253 | 0.75 | MAPT (0.60) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | ADH5, ADH1A, ADH1C | MAPT 3557/4885CYP1A2 169/4885CYP2C9 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.