Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | CA12 | O43570 | 6/20 | 0.66 |
| ▸ | CA9 | Q16790 | 6/20 | 0.66 |
| ▸ | CA1 | P00915 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | GAA | P10253 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | GLA | P06280 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361958 | 0.85 | ALDH1A1 (0.68) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL16266302 | 0.83 | ALDH1A1 (0.66) | ALDH1A1CA12CA9CA1LMNA | |
| Hydrochloric Acid SCHEMBL25373064 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL20870224 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL29176757 | 0.81 | ALDH1A1 (0.59) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL10134019 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL19022033 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL1034943 | 0.81 | CA12 (0.72) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL29673209 | 0.81 | CA12 (0.72) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL29738214 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA12CA9CA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | ALDH1A1 181/4885CA12 3628/4885CA9 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.