Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | CA12 | O43570 | 6/20 | 0.66 |
| ▸ | CA9 | Q16790 | 6/20 | 0.66 |
| ▸ | CA1 | P00915 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | GLA | P06280 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | CASP1 | P29466 | 2/20 | 0.63 |
| ▸ | CASP7 | P55210 | 2/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25373064 | 0.98 | ALDH1A1 (0.64) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL3361958 | 0.85 | ALDH1A1 (0.68) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL16316724 | 0.83 | ALDH1A1 (0.66) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL20870224 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL22685138 | 0.81 | CA12 (0.76) | ALDH1A1CA12CA9CA1KDM4E | |
| SCHEMBL10134019 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL19022033 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL1034943 | 0.81 | CA12 (0.72) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL29673209 | 0.81 | CA12 (0.72) | ALDH1A1CA12CA9CA1LMNA | |
| SCHEMBL29738214 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CA12CA9CA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015041729-A2 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF α-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2015-03-26 | — | — | WO | claimed |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-12-04 | — | — | US | claimed |
| US-11958880-B2 | Means and methods for site-specific functionalization of polypeptides | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2024-04-16 | — | — | US | disclosed |
| WO-2023164193-A1 | REAGENTS FOR FLUORESCENT, UV, AND MS LABELING OF O-GLYCANS, AND METHODS OF MAKING AND USING THEM | AGILENT TECHNOLOGIES, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-02-07 | — | — | US | disclosed |
| US-20220363714-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2022-11-17 | — | — | US | disclosed |
| US-11401298-B2 | Means and methods for site-specific functionalization of polypeptides | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2022-08-02 | — | — | US | disclosed |
| US-20210040145-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2021-02-11 | — | — | US | disclosed |
| EP-3733687-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | Ludwig-Maximilians-Universität München (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-10745437-B2 | Means and methods for site-specific functionalization of polypeptides | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2020-08-18 | — | — | US | disclosed |
| EP-3212659-B1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2020-04-01 | — | — | EP | disclosed |
| US-10071990-B2 | Site-specific orthogonal labeling of the carboxy terminus of α-tubulin in live cells | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-09-11 | — | — | US | disclosed |
| US-20170349625-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2017-12-07 | — | — | US | disclosed |
| WO-2017186855-A1 | UNUSUAL SUBSTRATES OF TUBULIN TYROSINE LIGASE | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2017-11-02 | — | — | WO | disclosed |
| EP-3212659-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | Ludwig-Maximilians-Universität München (DE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016066749-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2016-05-06 | — | — | WO | disclosed |
| WO-2015041729-A2 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF α-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2015-03-26 | — | — | WO | disclosed |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349625-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | PTMS, DNPEP, LNPEP | ALDH1A1 4561/4885CA12 1337/4885CA9 3514/4885 |
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | TTL, TUBA1C, TUBB6 | ALDH1A1 3975/4885CA12 3846/4885CA9 4469/4885 |
| US-20220363714-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | PTMS, DNPEP, LNPEP | ALDH1A1 4561/4885CA12 1337/4885CA9 3514/4885 |
| US-11401298-B2 | Means and methods for site-specific functionalization of polypeptides | PTMS, DNPEP, LNPEP | ALDH1A1 4561/4885CA12 1337/4885CA9 3514/4885 |
| US-20210040145-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | PTMS, DNPEP, LNPEP | ALDH1A1 4561/4885CA12 1337/4885CA9 3514/4885 |
| US-20140356894-A1 | SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF ALPHA-TUBULIN IN LIVE CELLS | TUBB, TUBA1C, TUBB1 | ALDH1A1 2392/4885CA12 3783/4885CA9 4428/4885 |
| US-10071990-B2 | Site-specific orthogonal labeling of the carboxy terminus of α-tubulin in live cells | TUBB, TUBA1C, TUBB1 | ALDH1A1 2407/4885CA12 3809/4885CA9 4448/4885 |
| US-10745437-B2 | Means and methods for site-specific functionalization of polypeptides | PTMS, DNPEP, LNPEP | ALDH1A1 4561/4885CA12 1337/4885CA9 3514/4885 |
| US-11958880-B2 | Means and methods for site-specific functionalization of polypeptides | PTMS, DNPEP, LNPEP | ALDH1A1 4561/4885CA12 1337/4885CA9 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.