Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632003 | 0.94 | NQO1 (0.43) | NQO1GABRA1GABRB2GABRB1FAAH | |
| SCHEMBL29350659 | 0.88 | GABRA1 (0.42) | NQO1GABRA1GABRB2GABRB1FAAH | |
| SCHEMBL15590876 | 0.88 | GABRA1 (0.42) | NQO1GABRA1GABRB2GABRB1FAAH | |
| SCHEMBL14327770 | 0.82 | GPR84 (0.39) | NQO1GABRA1GABRB2GABRB1FAAH | |
| SCHEMBL29805248 | 0.80 | GPR84 (0.36) | NQO1GABRA1GABRB2HPGDGPR84 | |
| SCHEMBL15590877 | 0.79 | CYP2A6 (0.35) | NQO1GABRA1GABRB2GABRB1FABP4 | |
| SCHEMBL28491890 | 0.75 | KMT2A (0.41) | GABRA1GABRB2LMNACYP1A2CYP3A4 | |
| Phosphonic Acid SCHEMBL31425585 | 0.75 | GPR84 (0.36) | NQO1GABRA1GABRB2GPR84KDM4E | |
| SCHEMBL16050488 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2GABRB1FAAHCA1 | |
| SCHEMBL16817000 | 0.75 | ROCK2 (0.38) | GABRA1GABRB2CYP1A2HPGDFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242240-B2 | Olefin metathesis catalysts and related methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150065723-A1 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-03-05 | — | — | US | disclosed |
| US-8829219-B2 | Olefin metathesis catalysts and related methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130281706-A1 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2013-10-24 | — | — | US | disclosed |
| US-8350073-B2 | Olefin metathesis catalysts and related methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110237815-A1 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-09-29 | — | — | US | disclosed |
| US-7932397-B2 | Molybdenum or tungsten complexed with such as 2,6-isopropylaniline, pyrrole and branched alkylidene; simple synthesis under mild conditions; high yield; wide variety from single precursor; one pot generation and chemical reaction use | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-04-26 | — | — | US | disclosed |
| WO-2008066754-A9 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | MASSACHUSETTS INST TECHNOLOGY (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008066754-A1 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080119678-A1 | Olefin metathesis catalysts and related methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065723-A1 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | APEX1, SQLE, COASY | NQO1 186/4885GABRA1 4282/4885GABRB2 4628/4885 |
| US-20110237815-A1 | OLEFIN METATHESIS CATALYSTS AND RELATED METHODS | APEX1, SQLE, COASY | NQO1 186/4885GABRA1 4282/4885GABRB2 4628/4885 |
| US-20080119678-A1 | Olefin metathesis catalysts and related methods | APEX1, SQLE, COASY | NQO1 186/4885GABRA1 4282/4885GABRB2 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.