Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15590876 | 0.90 | GABRA1 (0.42) | GPR84GABRA1GABRB2NQO1HPGD | |
| SCHEMBL29350659 | 0.90 | GABRA1 (0.42) | GPR84GABRA1GABRB2NQO1HPGD | |
| SCHEMBL16050488 | 0.83 | GABRA1 (0.52) | GABRA1GABRB2HPGDTSHRHIF1A | |
| SCHEMBL1632007 | 0.82 | NQO1 (0.45) | GPR84GABRA1GABRB2NQO1HPGD | |
| SCHEMBL28126975 | 0.81 | GABRA1 (0.50) | GABRA1GABRB2HPGDTSHRHIF1A | |
| SCHEMBL15590877 | 0.81 | CYP2A6 (0.35) | GPR84GABRA1GABRB2NQO1GABRB1 | |
| SCHEMBL1632003 | 0.80 | NQO1 (0.43) | GPR84GABRA1GABRB2NQO1HPGD | |
| SCHEMBL29805248 | 0.80 | GPR84 (0.36) | GPR84GABRA1GABRB2NQO1HPGD | |
| SCHEMBL14327786 | 0.77 | GPR84 (0.40) | GPR84NQO1HPGDTSHRHIF1A | |
| SCHEMBL14327758 | 0.75 | MEN1 (0.51) | GPR84NQO1HPGDTSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420847-B2 | Bis-phosphate compound and asymmetric reaction using the same | NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | API CORPORATION (JP) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | AASDHPPT, ALDH7A1, ATIC | GPR84 2802/4885GABRA1 2259/4885GABRB2 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.