Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827834 | 0.85 | MEN1 (0.41) | CYP1A2ALDH1A1TDP1MAPTALOX15 | |
| SCHEMBL21129793 | 0.85 | MEN1 (0.44) | CYP1A2ALDH1A1TDP1MAPTHTT | |
| SCHEMBL8460305 | 0.85 | SNCA (0.48) | CYP1A2ALDH1A1MAPTALOX15ALOX12 | |
| SCHEMBL23257600 | 0.84 | MAPT (0.46) | CYP1A2ALDH1A1TDP1MAPTHTT | |
| SCHEMBL31039440 | 0.84 | MAPT (0.46) | CYP1A2ALDH1A1TDP1MAPTHTT | |
| SCHEMBL26977016 | 0.83 | SNCA (0.47) | CYP1A2ALDH1A1TDP1MAPTALOX15 | |
| SCHEMBL19361406 | 0.83 | ALDH1A1 (0.46) | CYP1A2ALDH1A1TDP1MAPTALOX15 | |
| SCHEMBL18138434 | 0.82 | CYP1A2 (0.46) | CYP1A2ALDH1A1TDP1MAPTHTT | |
| SCHEMBL18069669 | 0.81 | ALOX15 (0.53) | CYP1A2ALDH1A1TDP1MAPTHTT | |
| SCHEMBL10759125 | 0.80 | ALDH1A1 (0.50) | CYP1A2ALDH1A1TDP1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264626-A1 | METHOD FOR PRODUCING PEPTIDE HYDRAZIDE, PEPTIDE AMIDE, AND PEPTIDE THIOESTER | AJINOMOTO CO., INC. (JP) | 2016-09-15 | — | — | US | disclosed |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-28 | — | — | US | disclosed |
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264626-A1 | METHOD FOR PRODUCING PEPTIDE HYDRAZIDE, PEPTIDE AMIDE, AND PEPTIDE THIOESTER | VIP, PPT1, NPPA | CYP1A2 2945/4885ALDH1A1 2688/4885TDP1 4253/4885 |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | CYP1A2 4860/4885ALDH1A1 4790/4885TDP1 4312/4885 |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | CYP1A2 4860/4885ALDH1A1 4790/4885TDP1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.