Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22732475 | 0.96 | DNM1 (0.37) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL12290350 | 0.96 | ALDH1A1 (0.38) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL2055305 | 0.92 | DNM1 (0.39) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL17126969 | 0.90 | KDM4A (0.36) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL14576169 | 0.89 | PHF8 (0.42) | DNM1KDM4AHIF1ATET2DOHH | |
| Poly(Amidoamine)Dendrimer SCHEMBL13964588 | 0.88 | DNM1 (0.37) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL8239576 | 0.88 | DNM1 (0.37) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL12904653 | 0.88 | KDM4A (0.35) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL17297337 | 0.87 | SLC6A5 (0.32) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL12219612 | 0.85 | KDM4A (0.38) | DNM1KDM4AHIF1ATET2DOHH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945508-B2 | Dendrimer compositions and methods of synthesis | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-02-03 | — | — | US | disclosed |
| US-20120259098-A1 | DENDRIMER COMPOSITIONS AND METHODS OF SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259098-A1 | DENDRIMER COMPOSITIONS AND METHODS OF SYNTHESIS | PAM, PAICS, PICALM | DNM1 9/4885KDM4A 4361/4885HIF1A 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.