Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719905 | 0.77 | ALOX5 (0.58) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL11558230 | 0.77 | PTGS1 (0.50) | KMT2AMEN1GAAMAPTALOX5 | |
| Sulfuric Acid SCHEMBL11106611 | 0.75 | ALOX5 (0.50) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL10829797 | 0.74 | MAPT (0.49) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL10971004 | 0.74 | ALDH1A1 (0.56) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL10918872 | 0.74 | KMT2A (0.47) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL10829800 | 0.74 | MAPT (0.49) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL7719890 | 0.73 | ALOX5 (0.58) | MAPTALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL13187322 | 0.72 | KMT2A (1.00) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL6778709 | 0.72 | SIGMAR1 (0.60) | KMT2AMEN1L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932247-B2 | M3 muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |
| US-20090149447-A1 | Novel M3 Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | US | disclosed |
| EP-1957075-A2 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-08-20 | — | — | EP | disclosed |
| WO-2006055553-A2 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-05-26 | — | — | WO | disclosed |
| EP-0055418-B1 | PYRAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-26 | — | — | EP | disclosed |
| US-4572913-A | INHIBITS ENZYMATIC PATHWAYS OF ARACHIONIC ACID METABOLISM | BURROUGHS WELLCOME CO. (US) | 1986-02-25 | — | — | US | disclosed |
| EP-0056465-B1 | PYRAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-09-04 | — | — | EP | disclosed |
| US-4465685-A | Antiinflammatory pyrazole thioureas | BURROUGHS WELLCOME CO. (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0056465-A2 | Pyrazoline derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-07-28 | — | — | EP | disclosed |
| EP-0055418-A2 | Pyrazoline derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149447-A1 | Novel M3 Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRM2, CHRNA3 | KMT2A 2049/4885MEN1 3696/4885L3MBTL1 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.