Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685361 | 0.84 | SLC18A3 (0.43) | SLC18A3SIGMAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL4839441 | 0.82 | ALDH1A1 (0.42) | SLC18A3SIGMAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL3183753 | 0.81 | SLC18A3 (0.43) | SLC18A3SIGMAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL236979 | 0.80 | TAAR1 (0.44) | SLC18A3SIGMAR1IDO1TDO2 | |
| SCHEMBL6683467 | 0.79 | LMNA (0.57) | SLC18A3SIGMAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL31138108 | 0.79 | LMNA (0.57) | SLC18A3SIGMAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL23364605 | 0.79 | RIPK1 (0.64) | SLC18A3SIGMAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8500559 | 0.79 | CYP1A2 (0.44) | CYP3A4CYP2D6ALDH1A1TSHRNFKB1 | |
| SCHEMBL8722245 | 0.79 | TAAR1 (0.49) | SLC18A3SIGMAR1SLC6A3CYP2D6SLC6A2 | |
| SCHEMBL16596410 | 0.79 | CYP1A2 (0.44) | CYP3A4CYP2D6ALDH1A1TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013782-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2018-10-03 | — | — | EP | disclosed |
| US-9708570-B2 | Organic compounds | Givaudan, S.A. (CH) | 2017-07-18 | — | — | US | disclosed |
| US-20160369205-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2016-12-22 | — | — | US | disclosed |
| EP-3013782-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014205782-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014207205-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160369205-A1 | ORGANIC COMPOUNDS | PAH, AQP3, HPD | AOC3 62/4885SLC18A3 3120/4885SIGMAR1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.