Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16335823 | 0.96 | SLC6A3 (0.47) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL20956451 | 0.84 | CA12 (0.49) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL5753898 | 0.82 | SLC6A3 (0.43) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL5753520 | 0.82 | KDM4E (0.50) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL29054652 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL19125964 | 0.81 | RXRA (0.42) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL3427457 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL18397725 | 0.79 | SLC6A3 (0.40) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL38659191 | 0.79 | KDM4E (0.49) | SLC6A3CA12CA1CA2CA7 | |
| SCHEMBL38658367 | 0.79 | KDM4E (0.49) | SLC6A3CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459019-B | Oxazoline compounds | 巴斯夫欧洲公司 | 2020-01-17 | — | — | CN | disclosed |
| US-10226045-B2 | Azoline compounds | BASF SE (DE) | 2019-03-12 | — | — | US | disclosed |
| EP-3110811-B1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2018-11-07 | — | — | EP | disclosed |
| US-20180235226-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2018-08-23 | — | — | US | disclosed |
| US-9968087-B2 | Azoline compounds | BASF SE (DE) | 2018-05-15 | — | — | US | disclosed |
| EP-3110811-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-20160366887-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2016-12-22 | — | — | US | disclosed |
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BASF SE (DE) | 2016-05-26 | — | — | US | disclosed |
| EP-3013820-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2015128358-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2015-09-03 | — | — | WO | disclosed |
| WO-2014206910-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BROX, TUBA3C, SYMPK | SLC6A3 3066/4885CA12 3805/4885CA1 2116/4885 |
| US-10226045-B2 | Azoline compounds | CCNB2, CCNB1, CYP1B1 | SLC6A3 4309/4885CA12 1928/4885CA1 1375/4885 |
| US-20160366887-A1 | AZOLINE COMPOUNDS | CCNB2, CCNB1, CYP1B1 | SLC6A3 4309/4885CA12 1928/4885CA1 1375/4885 |
| US-20180235226-A1 | AZOLINE COMPOUNDS | CCNB2, CCNB1, CYP1B1 | SLC6A3 4309/4885CA12 1928/4885CA1 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.