SCHEMBL16336374

SCHEMBL16336374

CCCC(C)(C)C(=CN(C)C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.33
ELANE P08246 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1524596 0.79 ELANE (0.33) ELANEMEN1KMT2ATDP1
SCHEMBL6447696 0.68 AKR1C3 (0.46) CYP2C9ELANEMEN1KMT2ATDP1
SCHEMBL6447697 0.68 AKR1C3 (0.46) CYP2C9ELANEMEN1KMT2ATDP1
SCHEMBL5264333 0.68 ALDH1A1 (0.40) ELANEMEN1KMT2ATDP1
SCHEMBL11000935 0.68 TDP1 (0.40) ELANEMEN1KMT2ATDP1
SCHEMBL276239 0.67
SCHEMBL28373746 0.66 ELANE (0.35) ELANEMEN1KMT2ATDP1
SCHEMBL10481805 0.65 ACLY (0.36) CYP2C9
SCHEMBL14244834 0.65 ACLY (0.44) MEN1KMT2ATDP1
SCHEMBL8420497 0.65 ACLY (0.44) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds L'OREAL (FR) 2021-09-28 US disclosed
US-9884004-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9814668-B2 Hair styling compositions comprising latex polymers L'OREAL (FR) 2017-11-14 US disclosed
US-9814669-B2 Hair cosmetic composition containing latex polymers and a silicone-organic polymer compound L'OREAL (FR) 2017-11-14 US disclosed
US-9795556-B2 Compositions and methods for treating hair L'OREAL (FR) 2017-10-24 US disclosed
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND L'OREAL (FR) 2016-06-23 US disclosed
US-20150004115-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004118-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, NACA, DPM1 CYP2C9 2925/4885ELANE 309/4885MEN1 655/4885
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND SUCLG1, NACA, EPM2A CYP2C9 726/4885ELANE 1882/4885MEN1 774/4885
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds SRM, KRT18, ODC1 CYP2C9 3871/4885ELANE 4842/4885MEN1 1812/4885
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, DPM1, NACA CYP2C9 1689/4885ELANE 514/4885MEN1 881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.