Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558082 | 1.00 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28445468 | 0.93 | APP (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8017131 | 0.85 | HSP90AA1 (0.63) | L3MBTL1TDP1HSP90AA1CNR1CNR2 | |
| SCHEMBL29042404 | 0.81 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5242462 | 0.80 | MAPK1 (0.46) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL5409936 | 0.79 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8643567 | 0.78 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6812421 | 0.77 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7944406 | 0.77 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7936769 | 0.77 | MAPT (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117085143-A | PROTACs nano blocking agent for estrogen receptor and preparation method and application thereof | 郑州大学 | 2023-11-21 | — | — | CN | claimed |
| CN-116332901-A | Raloxifene derivative with room temperature phosphorescence characteristic and application thereof | 华东理工大学 | 2023-06-27 | — | — | CN | claimed |
| CN-117085143-A | PROTACs nano blocking agent for estrogen receptor and preparation method and application thereof | 郑州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-116332901-A | Raloxifene derivative with room temperature phosphorescence characteristic and application thereof | 华东理工大学 | 2023-06-27 | — | — | CN | disclosed |
| US-20230190938-A1 | NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2023-06-22 | — | — | US | disclosed |
| CN-113614076-A | Estrogen receptor protein degradation agent | 密执安大学评议会 | 2021-11-05 | — | — | CN | disclosed |
| CN-112566666-A | Compounds targeting anti-cancer nuclear hormone receptors | 努瓦申生物公司 | 2021-03-26 | — | — | CN | disclosed |
| EP-3016947-B1 | BENZOTHIOPHENE DERIVATIVES AS ESTROGEN RECEPTOR INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-09-05 | — | — | EP | disclosed |
| EP-3016947-A1 | BENZOTHIOPHENE DERIVATIVES AS ESTROGEN RECEPTOR INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015000867-A1 | BENZOTHIOPHENE DERIVATIVES AS ESTROGEN RECEPTOR INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190938-A1 | NOVEL CARGO DELIVERY SYSTEM AND COMPOSITION COMPRISING THE SAME | ATG7, SQSTM1, BECN1 | TUBB4A 2378/4885TUBB 1605/4885TUBA3C 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.