SCHEMBL1634877

SCHEMBL1634877

[O]C(F)=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
LMNA P02545 1/20 0.33
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636011 0.97 THRB (0.46) THRBCA2CA1MMP1MMP2
SCHEMBL5365862 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL4924486 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL1019945 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL8380164 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL5374510 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL28212362 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL7638470 0.83 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL6892577 0.80 THRB (0.50) THRBCA2CA1MMP1MMP2
SCHEMBL7630035 0.80 THRB (0.48) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2290847-A None JP disclosed
JP-63165342-A None JP disclosed
US-20230323030-A1 Polyamide, Polyamide-Imide, Derivatives of These, Optical Film, Display Device, and Production Methods Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2023-10-12 US disclosed
US-20230303480-A1 Polybenzoxazole, Polyamide, Polyamide Solution, Insulating Material for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Equipment, Insulating Material for Producing High-Frequency Electronic Component, Method for Producing Polyamide, Method for Producing Polybenzoxazole, Method for Producing Insulating Material for High-Frequency Electronic Component, and Diamine or Salt Thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-28 US disclosed
US-20230287178-A1 Fluorinated Diamine or Salt Thereof, Method for Producing Fluorinated Diamine or Salt Thereof, Polyamide, Method for Producing Polyamide, Polyamide Solution, Cyclized Polyamide, Method for Producing Cyclized Polyamide, Insulation for High-Frequency Electronic Component, Method for Producing Insulation for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Appliance, and Insulating Material for Producing High-Frequency Electronic Component CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-14 US disclosed
EP-4194482-A1 POLYBENZOXAZOLE, POLYAMIDE, POLYAMIDE SOLUTION, INSULATION FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY EQUIPMENT, INSULATION MATERIAL FOR PRODUCING HIGH-FREQUENCY ELECTRONIC COMPONENT, METHOD FOR PRODUCING POLYAMIDE, METHOD FOR PRODUCING POLYBENZOXAZOLE, METHOD FOR PRODUCING INSULATION FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, AND DIAMINE OR SALT THEREOF Central Glass Company, Limited (JP) 2023-06-14 EP disclosed
EP-4190768-A1 FLUORINATED DIAMINE OR SALT THEREOF, METHOD FOR PRODUCING FLUORINATED DIAMINE OR SALT THEREOF, POLYAMIDE, METHOD FOR PRODUCING POLYAMIDE, POLYAMIDE SOLUTION, CYCLIZED POLYAMIDE, METHOD FOR PRODUCING CYCLIZED POLYAMIDE, INSULATING MATERIAL FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, METHOD FOR PRODUCING INSULATING MATERIAL FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY APPLIANCE, AND INSULATING MATERIAL FOR PRODUCING HIGH-FREQUENCY ELECTRONIC COMPONENT Central Glass Company, Limited (JP) 2023-06-07 EP disclosed
EP-4163319-A1 POLYAMIDE, POLYAMIDE-IMIDE, DERIVATIVES OF THESE, OPTICAL FILM, DISPLAY DEVICE, AND PRODUCTION METHODS THEREFOR Central Glass Company, Limited (JP) 2023-04-12 EP disclosed
CN-110511533-B Polyether-ether-ketone/tetrafluoroethylene-perfluoroalkoxy vinyl ether copolymer/chopped quartz fiber material, and preparation method and application thereof 吉林大学 2020-08-04 CN disclosed
CN-110511533-B Polyether-ether-ketone/tetrafluoroethylene-perfluoroalkoxy vinyl ether copolymer/chopped quartz fiber material, and preparation method and application thereof 吉林大学 2020-08-04 CN disclosed
US-20090023886-A1 Waterproofing; oil repellents; heat resistance; weatherproofing; corrosion resistance; radiation transparent; photosensitivity; low refractive index, dielectrics CENTRAL GLASS COMPANY, LIMITED (JP) 2009-01-22 US disclosed
EP-1810963-B1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME CENTRAL GLASS CO LTD (JP) 2008-10-15 EP disclosed
US-20080234460-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same CENTRAL GLASS CO., LTD. (JP) 2008-09-25 US disclosed
US-20080221298-A1 Fluorinated Diamine and Polymer Made from the Same CENTRAL GLASS COMPANY, LIMITED (JP) 2008-09-11 US disclosed
EP-1832618-A1 FLUORINATED DIAMINE AND POLYMER MADE FROM THE SAME Central Glass Company, Limited (JP) 2007-09-12 EP disclosed
EP-1810963-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME Central Glass Company, Limited (JP) 2007-07-25 EP disclosed
EP-1783158-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME Central Glass Company, Limited (JP) 2007-05-09 EP disclosed
US-5243019-A Heat resistant polymers HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-09-07 US disclosed
JP-H02290847-A BISMALEIMIDE COMPOUND HAVING PERFLUORONONENYLOXY GROUP, ITS PRODUCTION AND BISMALEIMIDE RESIN MATERIAL HITACHI CHEM CO LTD 1990-11-30 JP disclosed
JP-S63165342-A FLUORINE-CONTAINING COMPLEX NEOS CO LTD 1988-07-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234460-A1 Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same AFF2, FRG1, PFAS THRB 4570/4885CA2 1231/4885CA1 985/4885
US-20080221298-A1 Fluorinated Diamine and Polymer Made from the Same AFF1, AFF2, SAT1 THRB 3709/4885CA2 3877/4885CA1 1344/4885
US-20230303480-A1 Polybenzoxazole, Polyamide, Polyamide Solution, Insulating Material for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Equipment, Insulating Material for Producing High-Frequency Electronic Component, Method for Producing Polyamide, Method for Producing Polybenzoxazole, Method for Producing Insulating Material for High-Frequency Electronic Component, and Diamine or Salt Thereof PUF60, TET1, PBRM1 THRB 2340/4885CA2 352/4885CA1 333/4885
US-20090023886-A1 Waterproofing; oil repellents; heat resistance; weatherproofing; corrosion resistance; radiation transparent; photosensitivity; low refractive index, dielectrics PFN1, PFAS, FRG1 THRB 1746/4885CA2 3885/4885CA1 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.