SCHEMBL16355349

SCHEMBL16355349

c1ccc2cc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4cc(-c5ccc6nn(-c7ccc(-c8ccncc8)cc7)nc6c5)ccc34)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 14/20 0.39
MAPK9 P45984 12/20 0.39
MAPK8 P45983 4/20 0.38
CHEK1 O14757 1/20 0.36
PIK3CA P42336 1/20 0.36
ALOX5 P09917 1/20 0.36
ROCK2 O75116 1/20 0.35
CYP17A1 P05093 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
SRC P12931 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16355316 0.95 MAPK10 (0.42) MAPK10MAPK9MAPK8ALOX5
SCHEMBL16355374 0.91 MAPK10 (0.46) MAPK10MAPK9MAPK8ALOX5CYP17A1
SCHEMBL19529190 0.89 KDM4E (0.44) PIK3CAALOX5SRC
SCHEMBL15949831 0.89 CYP11B2 (0.52) MAPK9MAPK8CHEK1PIK3CACYP17A1
SCHEMBL30911063 0.89 CYP11B2 (0.52) MAPK9MAPK8CHEK1PIK3CACYP17A1
SCHEMBL16355367 0.89 GRM5 (0.41) MAPK10MAPK9MAPK8PIK3CACYP17A1
SCHEMBL15959617 0.88 PIK3CA (0.45) CHEK1PIK3CAROCK2
SCHEMBL17805222 0.87 CYP11B2 (0.49) MAPK9MAPK8CHEK1PIK3CACYP17A1
SCHEMBL17805188 0.86 PIK3CA (0.43) CHEK1PIK3CA
SCHEMBL17812843 0.85 CYP11B1 (0.44) PIK3CAALOX5ROCK2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
EP-3244462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3240057-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-01 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 MAPK10 710/4885MAPK9 679/4885MAPK8 2102/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 MAPK10 710/4885MAPK9 679/4885MAPK8 2102/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT MAPK10 714/4885MAPK9 528/4885MAPK8 1801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.