Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.50 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16027799 | 0.94 | TSHR (0.62) | ALDH1A1TSHRKDM4EPOLBLMNA | |
| SCHEMBL16363982 | 0.86 | TRPC5 (0.55) | ALDH1A1TSHRLMNATRPC4TRPC5 | |
| SCHEMBL19375261 | 0.85 | TSHR (0.66) | ALDH1A1TSHRKDM4EPOLBLMNA | |
| SCHEMBL29103734 | 0.84 | TSHR (0.61) | ALDH1A1TSHRKDM4EPOLBLMNA | |
| SCHEMBL18833614 | 0.82 | SMN1; SMN2 (0.63) | ALDH1A1TSHRKDM4EPOLBLMNA | |
| SCHEMBL16028290 | 0.81 | TRPC5 (0.60) | ALDH1A1TSHRPOLBLMNATRPC4 | |
| SCHEMBL27411457 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4EPOLBLMNA | |
| SCHEMBL16028784 | 0.79 | TRPC5 (0.64) | ALDH1A1TSHRPOLBLMNATRPC4 | |
| SCHEMBL16028537 | 0.79 | TRPC5 (0.63) | ALDH1A1TSHRPOLBLMNATRPC4 | |
| SCHEMBL16364235 | 0.79 | SMN1; SMN2 (0.77) | ALDH1A1TSHRKDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014143799-A9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2014-12-24 | — | — | WO | disclosed |