Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869978 | 0.79 | PTGS2 (0.51) | CXCL8AKR1B1TDP1PTGS2MEN1 | |
| SCHEMBL3304485 | 0.78 | TAAR1 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL503912 | 0.78 | AKR1B1 (0.56) | CXCL8AKR1B1PTGS2MEN1ALDH1A1 | |
| SCHEMBL25679309 | 0.78 | CXCL8 (0.53) | CXCL8AKR1B1TDP1PTGS2MEN1 | |
| SCHEMBL30558299 | 0.78 | CXCL8 (0.53) | CXCL8AKR1B1TDP1PTGS2MEN1 | |
| SCHEMBL723768 | 0.77 | CXCL8 (0.56) | CXCL8AKR1B1TDP1PTGS2KDM4E | |
| SCHEMBL18984003 | 0.77 | GABRA1 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL8127229 | 0.77 | TAAR1 (0.38) | MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL29533621 | 0.77 | CXCL8 (0.65) | CXCL8AKR1B1TDP1PTGS2MEN1 | |
| Hydrochloric Acid SCHEMBL1372001 | 0.77 | AKR1B1 (0.54) | CXCL8AKR1B1PTGS2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932376-B2 | Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| WO-2006121856-A2 | PYRIMIDINE-BASED NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20060258614-A1 | Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258614-A1 | Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation | P2RY12, P2RY11, P2RY13 | CXCL8 651/4885AKR1B1 1634/4885TDP1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.