Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911305 | 0.87 | PTGS2 (0.56) | PTGS2AKR1B1TDP1KDM4EMAPT | |
| SCHEMBL20045094 | 0.84 | PTGS2 (0.56) | PTGS2AKR1B1TDP1KDM4EMAPT | |
| SCHEMBL20045103 | 0.82 | PTGS2 (0.51) | PTGS2AKR1B1TDP1KDM4EMAPT | |
| SCHEMBL3767513 | 0.79 | GABRA1 (0.48) | PTGS2TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL1636607 | 0.79 | CXCL8 (0.50) | PTGS2AKR1B1TDP1KDM4EMAPT | |
| SCHEMBL7595125 | 0.78 | TAAR1 (0.37) | MAPTCYP1A2 | |
| SCHEMBL1004574 | 0.78 | KDM4E (0.58) | PTGS2AKR1B1KDM4EMAPTMEN1 | |
| SCHEMBL29933724 | 0.78 | PTGS2 (0.54) | PTGS2AKR1B1TDP1KDM4EMAPT | |
| SCHEMBL5925081 | 0.78 | PTGS2 (0.54) | PTGS2AKR1B1TDP1KDM4EMAPT | |
| SCHEMBL2552936 | 0.78 | PTGS2 (0.54) | PTGS2AKR1B1TDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160045626-A1 | Methods and Compositions for Improved Labeling of Targeting Peptides | IMMUNOMEDICS, INC. | 2016-02-18 | — | — | US | disclosed |
| US-9115172-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-9028800-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20150057432-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20140377177-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2014-12-25 | — | — | US | disclosed |
| US-8889100-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140228541-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8758726-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20130315821-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| US-8545809-B2 | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8444956-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-8398956-B2 | In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents | IMMUNOMEDICS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120282178-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-8202509-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120076727-A1 | In Vivo Copper-Free Click Chemistry for Delivery of Therapeutic and/or Diagnostic Agents | IMMUNOMEDICS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20110110854-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057432-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PTGS2 4745/4885AKR1B1 4347/4885TDP1 4434/4885 |
| US-20130315821-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PTGS2 4745/4885AKR1B1 4347/4885TDP1 4434/4885 |
| US-20110110854-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, F13A1, FCGRT | PTGS2 4799/4885AKR1B1 4102/4885TDP1 4399/4885 |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | PTGS2 4819/4885AKR1B1 4182/4885TDP1 4600/4885 |
| US-20140228541-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PTGS2 4745/4885AKR1B1 4347/4885TDP1 4434/4885 |
| US-20120282178-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, F13A1, FCGRT | PTGS2 4799/4885AKR1B1 4102/4885TDP1 4399/4885 |
| US-20120076727-A1 | In Vivo Copper-Free Click Chemistry for Delivery of Therapeutic and/or Diagnostic Agents | TIE1, C9, NCLN | PTGS2 3131/4885AKR1B1 2368/4885TDP1 2771/4885 |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | PTGS2 4819/4885AKR1B1 4182/4885TDP1 4600/4885 |
| US-20140377177-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | PTGS2 4819/4885AKR1B1 4182/4885TDP1 4600/4885 |
| US-20160045626-A1 | Methods and Compositions for Improved Labeling of Targeting Peptides | SSTR5, SSTR4, SSTR2 | PTGS2 4553/4885AKR1B1 4691/4885TDP1 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.