Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370882 | 0.88 | CYP1A2 (0.47) | MEN1KMT2AALDH1A1L3MBTL1FKBP1A | |
| SCHEMBL16370718 | 0.81 | SMN1; SMN2 (0.50) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16371043 | 0.80 | FKBP1A (0.49) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16370936 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL16371130 | 0.80 | SMN1; SMN2 (0.49) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL16370596 | 0.78 | SMN1; SMN2 (0.51) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16371037 | 0.77 | KMT2A (0.51) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8983621 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL16370542 | 0.74 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3936978 | 0.72 | PKM (0.59) | ALDH1A1LMNAL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | claimed |
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |